Adult Dose

4-5 mg/kg/day -
7mg/kg may be necessary in critically ill patients)
Split dose may be preferable in infective endocarditis,
Peak (3-5mg/L) and trough: < 1mg/l levels should be targeted
Ideal body weight (IBW) should be used for dose calculation

 

Pediatric Dose

4-5 mg/kg/day