05 Nov 2026

9.2 Impetigo

Type of Infection First Line
(with Dosage and Duration)
Alternative First Line
(with dosage and Duration)
Comments
Impetigo – localised skin involvement Topical antibiotic therapy: Mupirocin 2% ∓ Fusidic acid 2% for 7 days Wash skin, remove crust and use disinfectants.
Impetigo – extensive skin involvement, bullous disease and/or lymphadenopathy Topical antibiotic therapy: Mupirocin 2% ∓ Fusidic acid 2% for 7 days + Amoxicillin 500mg TDS (25-50 mg/kg/day) Or Amoxicillin- clavulanate 625mg q8h Cephalexin 500 mg every 6 hours for 5 days

For common etiological agents of Impetigo, see Annexure B.9.2

References

1. Griffiths, C.E.M. and Barker, J. and Bleiker, T.O. and Hussain, W. and Simpson, R.C. Rook's Textbook of Dermatology. 10th Edition 2024. United Kingdom: Wiley.