05 Nov 2026

6.7 Prostatitis

Type of Infection First Line
(with Dosage and Duration)
Alternative First Line
(with dosage and Duration)
Comments
Acute Prostatitis (seen in young, sexually active with no structural urinary tract abnormality) Ceftriaxone 500 IM Stat + Doxycycline 100mg BD for 10 days Tab Cefixime 800mg stat + Doxycycline 100mg BD for 10 days
Acute Prostatitis (seen in elderly or with persons with structural urinary tract abnormality) Amoxicillin- clavulanate 1g BD Or Piperacillin- tazobactam 4.5g IV 6 hrly Ertapenem 1g IV OD for 7-10 days Urine and prostatic massage specimen for cultures to be collected before antibiotics. Duration of therapy 14 days or longer if complications like abscess present.

For common etiological agents of Prostatitis, see Annexure B.6.7

Additional Information

  1. Review antibiotic treatment after 14 days and either stop antibiotics or continue further if needed (based on assessment of history, symptoms, clinical examination, urine and blood tests).
  2. A stop date should be planned and recorded in advance to ensure antibiotic is not given beyond the recommended duration.