05 Nov 2026

5.2 Pyelonephritis

Type of Infection First Line
(with Dosage and Duration)
Alternative First Line
(with dosage and Duration)
Comments
Acute Pyelonephritis Piperacillin- tazobactam 4.5g IV q6h for 7-10 days Ertapenem 1g IV/IM q24h for 7-10 days Or Inj Cefoperazone- sulbactam 3g IV BD Or Inj Amikacin 15mg/kg IV OD Collect urine and blood specimens prior to the administration of antibiotics. Change the empiric regimen based on susceptibility testing.

For common etiological agents of Pyelonephritis, see Annexure B.5.2