05 Nov 2026

4.9 Pancreatitis

Type of Infection First Line
(with Dosage and Duration)
Alternative First Line
(with dosage and Duration)
Comments
Pancreatitis without infection No antibiotics Surgery opinion to be taken.
Infected pancreatic necrosis, Infected pseudocyst Piperacillin- tazobactam 4.5g IV q6h (To stop after 5- 7 days of source control initiation) Imipenem- cilastatin 500mg IV q6h Or Meropenem 1g IV q8h (To stop after 5-7 days of source control initiation) Surgery opinion to be taken Therapy to be adjusted as per the culture and sensitivity results from pancreatic aspirate or necrosectomy. Antifungal cover with fluconazole, or echinocandins like Caspofungin/ Micafungin may be added if risk factors for disseminated candidiasis are present.

For common etiological agents of Pancreatitis, see Annexure B.4.9

References

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