4.7 Peritonitis – Primary / Secondary
| Type of Infection | First Line (with Dosage and Duration) |
Alternative First Line (with dosage and Duration) |
Comments |
|---|---|---|---|
| Spontaneous Bacterial Peritonitis | Piperacillin- tazobactam 4.5g IV q6h for 7-10 days | Cefoperazone- sulbactam 3g IV q12h | Optimize therapy based on culture and susceptibility results. |
| Secondary peritonitis | Piperacillin- tazobactam 4.5g IV q6h Or Cefoperazone- sulbactam 3g IV q12h Or Ertapenem 1g IV q24h | Meropenem 1g IV q8h Or Imipenem- cilastatin 500mg IV q6h | Surgical drainage is required. Duration of therapy: 5-7 days (surgical drainage done and no complications like persistent abscess/collection identified). |
For common etiological agents of Peritonitis – Primary / Secondary, see Annexure B.4.7