4.6 Diverticulitis
| Type of Infection | First Line (with Dosage and Duration) |
Alternative First Line (with dosage and Duration) |
Comments |
|---|---|---|---|
| Diverticulitis without features of sepsis | Ceftriaxone 2g IV q24h + Inj Metronidazole 500 mg IV q8h Or Tab Cefixime 400 mg BD + Metronidazole 400 mg TDS | Piperacillin-tazobactam 4.5 g IV q6h Or Cefoperazone- sulbactam 3g IV q12h Or Ertapenem 1g IV q24h | Ceftriaxone to be changed to oral cefixime when patient is afebrile. BL-BLI agents and carbapenems have very good anaerobic cover, so no need to add metronidazole. Duration of therapy: 5-7 days |
| Diverticulitis with features of sepsis | Meropenem 1g IV q8h Or Imipenem-cilastatin 500mg IV q6h | Duration of therapy: 5-7 days |
For common etiological agents of Diverticulitis, see Annexure B.4.6