4.5 Appendicitis
| Type of Infection | First Line (with Dosage and Duration) |
Alternative First Line (with dosage and Duration) |
Comments |
|---|---|---|---|
| Appendicitis without any abscess | Amoxicillin-clavulanic Acid 1.2g IV q8h for 5 days | Inj Ceftriaxone 2g IV OD + Inj Metronidazole 500 mg IV q8h | Surgery is the preferred choice of management. In case of conservative management, antibiotics to be given for 5 days. |
| Complicated (Appendicitis with high severity and or Abscess) | Inj Piperacillin- tazobactam 4.5g IVq6h Or Inj Cefoperazone- sulbactam 3g IV q12h for 7-10 days | Imipenem-cilastatin 500mg IV q6h Or Meropenem 1g IV q8h for 5 days | Surgery is the primary mode of treatment. |
For common etiological agents of Appendicitis, see Annexure B.4.5
Additional Information
- In early stages of infection, the growth is mainly of aerobic organisms, but as the disease progresses, it transitions to a mix of aerobic and anaerobic bacteria.