05 Nov 2026

18.1 Fever in ICU

Type of Infection First Line
(with Dosage and Duration)
Alternative First Line
(with dosage and Duration)
Comments
Fever in ICU can be due to infective or non-infective causes. Empiric therapy for HAI would depend upon the infectious syndrome, organism prevalent in the unit, local resistance pattern For empirical antibiotic recommendations – refer to respective sections / tables as per suspected site of infections Common infectious causes include ventilator- associated pneumonia, catheter-related bloodstream infections, catheter associated urinary tract infections, surgical site infections, and hospital onset bacteremia from any other source. Draw two sets (each set having 1 aerobic and 1 anaerobic bottle) of blood cultures, from two different sites before starting treatment with antimicrobials. De-escalation should be done once the culture reports are available.

For common etiological agents of Fever in ICU, see Annexure B.18.1