Treatment of choice as per clinical syndrome

Clinical Syndrome Treatment options
Uncomplicated cystitis Trimethoprim-sulfamethoxazole
Nitrofurantoin
Oral Fosfomycin (single dose)
Single-dose aminoglycoside
Pyelonephritis and complicated Urinary Tract Infections Choose therapy as per discussion above
  • Do-not use Tigecycline or Polymyxin B
Infections outside urinary tract Choose therapy as per discussion above
  • Tigecycline is an acceptable alternative in patients with intra-abdominal infections 
  • Avoid using aminoglycosides for lung and intra-abdominal infection (use if other options are not available)