Horizontal interventions (for all patients)

1. Standard precautions including hand-hygiene
2. Adherence to device insertion and maintenance bundles for prevention of device related infections (VAP/CLABI/CAUTI)

Vertical Interventions (for patients infected or colonized with CRE, CRAP, CRPA)

1. Isolating these patients or cohorting (if many patients with same organism) into a single room or separate area
2. Following contact precautions as per WHO guidelines
3. Active surveillance (rectal samples) to look for CRE and subsequently isolating these patients can be done as a part of hospital policy to mitigate the spread of such organisms