Indication for surgery in patient with associated condition

Indication for surgery Timing
Heart failure  
Aortic/mitral IE with severe regurgitation/valve obstruction causing pulmonary oedema or cardiogenic shock Emergency
Aortic/mitral IE with fistula into cardiac chamber or pericardium causing refractory pulmonary oedema or shock Emergency
Aortic/mitral IE with severe acute regurgitation or valve obstruction and persisting heart failure or echocardiographic signs of poor hemodynamic tolerance Urgent
Aortic /mitral IE with severe regurgitation and no HF Elective
Uncontrolled Infection  
Locally uncontrolled infection (abscess/aneurysm/fistula/enlarging vegetation) Urgent
Persisting fever and positive blood culture >7-10 days Urgent
Infection caused by fungi or multiresistant organism Urgent
Prevention of Embolism  
Aortic/mitral IE with large vegetation(>10mm) following episode of embolism despite appropriate antibiotic therapy Urgent
Aortic/mitral IE with large vegetation(>10mm) and predictor of a complicated course Urgent
Isolated very large vegetation(>15mm) Urgent