Post-operative infections following solid organ transplant

Post-operative infections following solid organ transplant

Post-operative infections following solid organ transplant

Clinical condition	Common pathogens	Empirical antimicrobial agents	Alternative antimicrobial agents	Comments
Post-operative fever without hemodynamic instability	Usually of non-infectious etiology	None		Rule out non-infectious causes, hematoma, DVT, transfusion fever, etc.
Surgical site infection	S. aureus, Enterobacteriaceae, P. aeruginosa			Treatment based on culture results
VAP/HAP	P. aeruginosa, Acinetobacter spp, Enterobacteriaceae	Piperacillin-tazobactam or Cefoperazone-sulbactam		CR cover may be considered based on local epidemiology or culture results
CLABSI	S. aureus, Enterobacteriaceae, P. aeruginosa, Acinetobacter spp	Imipenem-cilastatin or meropenem or Cefoperazone-sulbactam plus Vancomycin	Cefoperazone-sulbactam plus Vancomycin	CR cover may be considered based on local epidemiology
CAUTI	Enterobacteriaceae, P. aeruginosa, enterococci	Piperacillin-tazobactam  or Cefoperazone-sulbactam	Imipenem-cilastatin or meropenem	Collect urine for culture before antibiotics

 

---