Which tests should be recommended for rapid diagnosis of C. difficle

Tests should not be performed for asymptomatic patients & do not perform repeat testing (within 7 days) during the same episode of diarrhoea .

Sensitivity and specificity of the diagnostic methods for CDI

Sensitivity

Specificity

Glutamate dehydrogenase [GDH] plus C. difficile toxic A & B assays 60-90% 76-98%
Xpert C. difficile assay (Xpert CD assay; Cepheid ) 90-100% 94.6-100%